Quick Study: Introduction to Tuberous Sclerosis Complex (TSC) and Epilepsy

APRIL 3 - MAY 8, 2025 | 12:00 PM - 1:00 PM (EST) | THURSDAYS WEEKLY
Tuberous sclerosis complex (TSC) is a multisystem disorder that can cause both epilepsy related and non-epilepsy related complications that family care providers may encounter. This curriculum aims to provide evidence-based education regarding management and treatment of TSC, TSC-associated epilepsy and other TSC comorbidities for health care providers caring for children and youth, and adults living with epilepsy.
Next Session
April 24, 2025
12:00 pm – 1:00 pm
S4. Tuberous Sclerosis Associated Neuropsychiatric Disorder

Case Support
Healthcare providers can present your de-identified case for advice, support and written recommendations.


This Quick Study series is facilitated by epilepsy specialists from the Children’s Hospital of Eastern Ontario (CHEO) and McMaster Children’s Hospital.
Syllabus
- Review the clinical diagnostic criteria for TSC, including dermatological findings
- Describe the genetic components associated with TSC and implications for patient care
- Describe the mechanism of action and indications for Everolimus in TSC treatment
- Discuss the use of Everolimus for epilepsy, subependymal giant cell astrocytomas (SEGA), and AMLs
- Explain the use of Vigabatrin in treating epilepsy associated with TSC
- Discuss the efficacy and safety profiles of other standard ASMs in TSC
- Define TAND and identify its manifestations in patients with TSC
- Understand the contribution of epilepsy and ASM use to neuropsychiatric symptoms
- Discuss management strategies to address TAND in clinical practice
- Review surgical options, including indications and outcomes, for epilepsy management in TSC
- Discuss non-surgical treatments for management of refractory epilepsy
- Recognize renal angiomyolipomas (AML) and other renal manifestations of TSC
- Assess the impact of ASM medications on renal function in patients with TSC
Didactics & Recordings
Clinical Leads

Dr. Katherine Muir, Paediatric Neurologist
Medical Co-Lead | CHEO

Nevena Simic, Neuropsychologist
McMaster Children's Hospital

Jennifer Flinn, Principal (Ottawa)
TSC Canada representative
Register
NOTE: Zoom Registration is working, you will receive a Zoom email confirming registration after you complete the form. However you may also receive this onscreen message “echo.zoom.us refused to connect” after registering. Do not be concerned, we are looking into this issue. But please email us at epilepsy@echoontario.ca if you do not receive the Zoom Registration Confirmation Email within 5 minutes of registering.